Nicotine absorption from electronic cigarette use: comparison between first and new-generation devices

There was a study that has compared the effect of using first- vs. new-generation EC devices on nicotine absorption. An 18 mg/ml nicotine-containing liquid was used, which is a popular “strength” consumed by experienced vapers and is close to the maximum level set by the European Commission regulatory proposal. Experienced vapers were recruited, who use the EC devices more intensively compared to novice users7. The results of the study showed that new-generation devices with high wattage output to the atomizer resulted in higher plasma nicotine levels compared to first-generation devices. However, both devices delivered to the bloodstream far lower nicotine compared to a tobacco cigarette. The study was funded by American E-Liquid Manufacturing Standards Association (AEMSA). Authors: Konstantinos E. Farsalinos, Alketa Spyrou,Kalliroi Tsimopoulou, Christos Stefopoulos,Giorgio Romagna & Vassilis Voudris.